Description

Pmc-S-Methylisothiourea CAS NO 185674-98-0 is a protected, high-purity thiourea derivative widely used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the S-methylisothiourea moiety while maintaining orthogonal protection for other functional groups. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of guanidine-containing drug candidates, including protease inhibitors and cardiovascular agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require the S-methylisothiourea functional group.
• Peptide Chemistry: Serves as a reagent for the selective modification of peptides and the synthesis of peptide mimetics.
• Chemical Biology Research: Employed in the development of enzyme inhibitors and molecular probes for studying biological pathways.
• Material Science: Potential precursor for the synthesis of functional polymers and specialty chemicals with tailored properties.

Basic Information

Product Name	Pmc-S-Methylisothiourea
CAS No.	185674-98-0
Molecular Formula	C11H16N2O2S
Molecular Weight	240.32 g/mol
Synonyms	S-Methyl-N-[(2,2,5,7,8-pentamethyl-3,4-dihydro-2H-1-benzopyran-6-yl)sulfonyl]isothiourea; 2,2,5,7,8-Pentamethylchroman-6-sulfonyl S-methylisothiourea; Pmc-SMeisothiourea; S-Methyl-N-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)isothiourea; N-(2,2,5,7,8-Pentamethyl-3,4-dihydro-2H-chromene-6-sulfonyl)-S-methylisothiourea; Pmc-S-methyl pseudothiourea; 6-[(Aminomethylsulfanylidene)sulfamoyl]-2,2,5,7,8-pentamethyl-3,4-dihydro-2H-chromene
EINECS	Contact for details

Quality Control

Our Pmc-S-Methylisothiourea is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and specifications can be aligned with customer-specific requirements for advanced R&D and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.