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Trimethyl Silyl-7-Ethyl Tryptophol CAS NO 185453-89-8


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CAS No.:185453-89-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Trimethyl Silyl-7-Ethyl Tryptophol is a specialized organosilicon derivative of tryptophol, designed for advanced synthetic applications. This high-purity intermediate is critical for researchers and manufacturers requiring precise molecular modifications in complex organic syntheses. It is primarily utilized in the pharmaceutical and fine chemical industries for the development of novel active pharmaceutical ingredients (APIs) and sophisticated chemical probes.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic compounds and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
  • Organic Synthesis Reagent: Used as a versatile reagent for introducing the protected tryptophol moiety in complex multi-step synthetic routes.
  • Chemical Research & Development: Serves as a valuable substrate for method development and exploration of new reaction pathways in academic and industrial R&D laboratories.
  • Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including advanced materials and agrochemical intermediates.
  • Protecting Group Strategy: The trimethylsilyl group acts as a protective group for sensitive functional groups during synthetic sequences.

Basic Information

Product Name Trimethyl Silyl-7-Ethyl Tryptophol
CAS No. 185453-89-8
Molecular Formula C15H23NOSi
Molecular Weight 261.44 g/mol
Synonyms 7-Ethyl-1H-indole-3-ethanol, 1-(trimethylsilyl)-; 1-(Trimethylsilyl)-7-ethyl-1H-indole-3-ethanol; 7-Ethyl-1-(trimethylsilyl)-1H-indole-3-ethanol; 7-Ethyl-1-trimethylsilyltryptophol; TMS-7-Ethyl Tryptophol; Trimethyl(7-ethyl-3-(2-hydroxyethyl)-1H-indol-1-yl)silane; 7-Ethyl-1-trimethylsilylindole-3-ethanol
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Quality Control

Our Trimethyl Silyl-7-Ethyl Tryptophol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development and cGMP manufacturing requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Purity (GC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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