Description

3-Chloro-2-(4-Chlorophenyl)-4,4,4-Trifluorobut-2-Enal 98 is a high-purity, halogenated trifluoromethylated aldehyde building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of chlorine and trifluoromethyl groups can dramatically alter biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, including potential pharmaceuticals, crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Serves as a key precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Research: Used in the synthesis of specialty polymers and liquid crystals where specific halogen and fluorine substitutions are required for desired electronic or physical properties.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-Chloro-2-(4-Chlorophenyl)-4,4,4-Trifluorobut-2-Enal 98
CAS No.	185389-58-6
Molecular Formula	C10H5Cl2F3O
Molecular Weight	269.05 g/mol
Synonyms	3-Chloro-2-(4-chlorophenyl)-4,4,4-trifluorobut-2-enal; 4,4,4-Trifluoro-3-chloro-2-(4-chlorophenyl)but-2-enal; 2-Butenal, 3-chloro-2-(4-chlorophenyl)-4,4,4-trifluoro-; (E)-3-Chloro-2-(4-chlorophenyl)-4,4,4-trifluorobut-2-enal; 3-Chloro-2-(p-chlorophenyl)-4,4,4-trifluorocrotonaldehyde; 185389-58-6; 4,4,4-Trifluoro-3-chloro-2-(4'-chlorophenyl)crotonaldehyde
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(4-Chlorophenyl)-4,4,4-Trifluorobut-2-Enal 98 is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and agrochemical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening sealed containers. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.