Description

5-Nitro-2-(Trimethylstannyl)-Pyridine is a specialized organotin compound featuring a nitro-substituted pyridine ring, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the nitro group offers a site for further chemical transformation and the trimethylstannyl group acts as a versatile handle for cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in constructing complex heterocyclic frameworks for potential therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the pyridine core is a common structural motif.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for catalysts or components in organic semiconductors.
• Cross-Coupling Reactions: Serves as a stannylating agent in Stille cross-coupling reactions to form new carbon-carbon bonds, a fundamental step in constructing complex organic molecules.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or molecular probes for biochemical and diagnostic research applications.
• Ligand Preparation: Acts as a starting material for the synthesis of specialized ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	5-Nitro-2-(Trimethylstannyl)-Pyridine
CAS No.	184962-91-2
Molecular Formula	C8H12N2O2Sn
Molecular Weight	286.89 g/mol
Synonyms	2-(Trimethylstannyl)-5-nitropyridine; 5-Nitro-2-trimethylstannylpyridine; Pyridine, 5-nitro-2-(trimethylstannyl)-; Trimethyl(5-nitro-2-pyridinyl)stannane; (5-Nitropyridin-2-yl)trimethylstannane; Stannane, trimethyl(5-nitro-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 5-Nitro-2-(Trimethylstannyl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Tin (Sn) Content	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.