Description

Ethyl 6-Oxo-4-(Trifluoromethyl)Hexahydropyridazine-3-Carboxylate is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in the trifluoromethyl group, which is strategically incorporated into target molecules to enhance their metabolic stability, lipophilicity, and binding affinity. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the CF3 group improves biological activity and environmental persistence.
• Fluorine Chemistry: Serves as a versatile scaffold for introducing fluorine atoms into complex molecular architectures in medicinal and materials chemistry.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke fine chemicals for client projects.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental research in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	Ethyl 6-Oxo-4-(Trifluoromethyl)Hexahydropyridazine-3-Carboxylate
CAS No.	184956-73-8
Molecular Formula	C9H11F3N2O3
Molecular Weight	252.19 g/mol
Synonyms	Ethyl 4-(trifluoromethyl)-6-oxohexahydropyridazine-3-carboxylate; 3-Carbethoxy-4-trifluoromethyl-2,3,4,5-tetrahydropyridazin-6-one; 4-(Trifluoromethyl)-2,3,4,5-tetrahydro-6H-pyridazin-6-one-3-carboxylic Acid Ethyl Ester; 1,4,5,6-Tetrahydropyridazine-3-carboxylic acid, 4-(trifluoromethyl)-6-oxo-, ethyl ester; Ethyl 4-(trifluoromethyl)-1,4,5,6-tetrahydropyridazine-3-carboxylate 6-oxide
EINECS	Contact for details

Quality Control

Our Ethyl 6-Oxo-4-(Trifluoromethyl)Hexahydropyridazine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.