Description

tert-Butyl 3-(Acetylsulfanyl)Azetidine-1-Carboxylate is a high-purity, protected azetidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the functionalized azetidine ring system, a key structural motif in modern medicinal chemistry. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of azetidine-containing drug candidates, particularly in areas like kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the azetidine scaffold can confer specific biological activity.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled compounds or probes used to study biological pathways and protein interactions.
• Peptidomimetics: Employed in the design and synthesis of peptidomimetic compounds, where the azetidine ring acts as a constrained amino acid surrogate.
• Material Science Research: Potential monomer or precursor for creating specialized polymers with unique properties derived from the heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	tert-Butyl 3-(Acetylsulfanyl)Azetidine-1-Carboxylate
CAS No.	183800-74-0
Molecular Formula	C10H17NO3S
Molecular Weight	231.31 g/mol
Synonyms	1-Boc-3-(acetylthio)azetidine; 3-(Acetylthio)-1-azetidinecarboxylic acid 1,1-dimethylethyl ester; 3-(Acetylsulfanyl)azetidine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-(acetylthio)azetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-(acetylthio)azetidine; Azetidine-1-carboxylic acid, 3-(acetylsulfanyl)-, 1,1-dimethylethyl ester; 3-Acetylthioazetidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(Acetylsulfanyl)Azetidine-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.