Description

3-(Hydroxymethyl)Cyclobutan-1-One is a versatile and synthetically valuable cyclobutane derivative. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is particularly sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers with unique thermal or mechanical properties.
• Fragrance & Flavor Chemistry: Utilized as an intermediate for synthesizing specific musky or woody odorant molecules.
• Academic & Industrial R&D: A valuable reagent for methodological studies in ring-opening and functionalization chemistry of strained carbocycles.

Basic Information

Product Name	3-(Hydroxymethyl)Cyclobutan-1-One
CAS No.	183616-18-4
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	3-(Hydroxymethyl)cyclobutanone; 3-Hydroxymethylcyclobutan-1-one; Cyclobutanone, 3-(hydroxymethyl)-; 3-Cyclobutanone methanol; 1-Oxaspiro[2.3]hexan-5-ol (tautomeric form); Hydroxymethyl cyclobutanone
EINECS	Contact for details

Quality Control

Our 3-(Hydroxymethyl)Cyclobutan-1-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment to ensure it meets your precise research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.