Description

(R)-(3-Pyrrolidineoxy)Tetrahydro-2H-Pyran is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. Pharmaceutical, agrochemical, and specialty chemical R&D teams need this material for its utility in asymmetric synthesis and as a precursor to pharmacologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Used in the synthesis of advanced, enantiomerically pure crop protection agents and herbicides.
• Material Science: Serves as a monomer or functionalization agent in the development of specialized polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(R)-(3-Pyrrolidineoxy)Tetrahydro-2H-Pyran
CAS No.	183540-38-7
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(R)-3-(Tetrahydro-2H-pyran-2-yloxy)pyrrolidine; (R)-3-(Oxan-2-yloxy)pyrrolidine; (R)-N-Boc-3-hydroxypyrrolidine THP ether; (3R)-3-[(Oxan-2-yl)oxy]pyrrolidine; (R)-3-(Tetrahydropyran-2-yloxy)pyrrolidine; Pyrrolidine, 3-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3R)-; (R)-N-Boc-3-(tetrahydropyran-2-yloxy)pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-(3-Pyrrolidineoxy)Tetrahydro-2H-Pyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.