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1,2,3,6-Tetra-o-Acetyl-4-Deoxy-4-Fluoro-D-Galactopyranose CAS NO 183506-73-2


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CAS No.:183506-73-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2,3,6-Tetra-o-Acetyl-4-Deoxy-4-Fluoro-D-Galactopyranose is a key fluorinated carbohydrate intermediate, specifically a protected galactose derivative. This compound is essential for introducing fluorine atoms into sugar molecules, a critical modification in medicinal chemistry and drug discovery. It is primarily used by researchers and manufacturers in the pharmaceutical industry for the synthesis of novel nucleoside analogs, glycomimetics, and other bioactive molecules.

Application

  • Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated nucleoside analogs with potential antiviral or anticancer activity.
  • Glycomimetics Development: Used in research to create stable sugar mimics that resist enzymatic degradation for therapeutic applications.
  • Probe and Diagnostic Agent Synthesis: Serves as a precursor for 18F-labeled compounds used in Positron Emission Tomography (PET) imaging.
  • Carbohydrate Chemistry Research: A valuable reagent for studying the effects of fluorination on glycosidic bond stability and biological activity.
  • Antibiotic Modification: Potential use in the structural modification of aminoglycoside or macrolide antibiotics to enhance properties.
  • Enzyme Inhibitor Design: Employed in the development of glycosidase or glycosyltransferase inhibitors.

Basic Information

Item Detail
Product Name 1,2,3,6-Tetra-o-Acetyl-4-Deoxy-4-Fluoro-D-Galactopyranose
CAS No. 183506-73-2
Molecular Formula C14H19FO9
Molecular Weight 350.29 g/mol
Synonyms 4-Deoxy-4-fluoro-D-galactose tetraacetate; 4-Fluoro-4-deoxy-D-galactopyranose tetraacetate; 1,2,3,6-Tetra-O-acetyl-4-deoxy-4-fluoro-D-galactopyranose; 4-Fluoro-D-galactose tetraacetate; Tetra-O-acetyl-4-deoxy-4-fluoro-D-galactopyranose; 4-Deoxy-4-fluoro-1,2,3,6-tetra-O-acetyl-D-galactopyranose; 4-Fluoro-4-deoxy-D-galactose 1,2,3,6-tetraacetate
EINECS Contact for details

Quality Control

Our 1,2,3,6-Tetra-o-Acetyl-4-Deoxy-4-Fluoro-D-Galactopyranose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and specific optical rotation measurement, to ensure high chemical purity and correct stereochemical configuration. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider using a desiccator.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Specific Optical Rotation Contact for details
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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