Description

(S)-4-Ethyl-4-Hydroxy-3,8-Dioxo-3,4,7,8-Tetrahydro-1H-Pyrano[3,4-C]Pyridine-6-Carboxylic Acid Propyl Ester is a high-purity, chiral organic compound belonging to the pyranopyridine class, serving as a critical advanced pharmaceutical intermediate. Its defined stereochemistry and complex heterocyclic structure make it essential for the synthesis of targeted active pharmaceutical ingredients (APIs) with specific biological activity. This compound is primarily required by R&D laboratories and production facilities in the pharmaceutical and fine chemical industries for the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and anti-infective research.
• Chiral Synthesis: Utilized in asymmetric synthesis to construct complex molecules with defined stereocenters for medicinal chemistry applications.
• Chemical Research: Serves as a reference standard and a starting material for method development and structure-activity relationship (SAR) studies.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A foundational compound for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules for clients.

Basic Information

Product Name	(S)-4-Ethyl-4-Hydroxy-3,8-Dioxo-3,4,7,8-Tetrahydro-1H-Pyrano[3,4-C]Pyridine-6-Carboxylic Acid Propyl Ester
CAS No.	183434-02-8
Molecular Formula	C16H19NO6
Molecular Weight	321.33 g/mol
Synonyms	(S)-4-Ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester; Propyl (S)-4-ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridine-6-carboxylate; 1H-Pyrano[3,4-c]pyridine-6-carboxylic acid, 4-ethyl-3,4,7,8-tetrahydro-4-hydroxy-3,8-dioxo-, propyl ester, (S)-; CAS 183434-02-8
EINECS	Contact for details

Quality Control

Our (S)-4-Ethyl-4-Hydroxy-3,8-Dioxo-3,4,7,8-Tetrahydro-1H-Pyrano[3,4-C]Pyridine-6-Carboxylic Acid Propyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing specific results for purity, chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.