Description

2H-Pyran-2-One, Tetrahydro-3-(Trifluoroacetyl)-, (+)- (9Ci) is a high-value, optically active lactone derivative characterized by its trifluoroacetyl functional group. This compound serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis, enabling the introduction of both stereochemistry and fluorine-containing motifs. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fluorine Chemistry Studies: Serves as a model compound for investigating the reactivity and incorporation of trifluoroacetyl groups into complex molecular architectures.
• Fine Chemical Production: Acts as a precursor for the synthesis of specialty flavors, fragrances, and other high-value fine chemicals requiring specific stereochemistry.
• Material Science Research: Potential monomer or building block for developing novel polymers with unique optical or surface properties.

Basic Information

Product Name	2H-Pyran-2-One, Tetrahydro-3-(Trifluoroacetyl)-, (+)- (9Ci)
CAS No.	183279-74-5
Molecular Formula	C7H7F3O3
Molecular Weight	196.13 g/mol
Synonyms	(+)-Tetrahydro-3-(trifluoroacetyl)-2H-pyran-2-one; (3R)-3-(Trifluoroacetyl)tetrahydro-2H-pyran-2-one; (R)-3-(Trifluoroacetyl)dihydro-2H-pyran-2(3H)-one; 3-(Trifluoroacetyl)dihydro-2H-pyran-2(3H)-one, (R)-; 183279-74-5; (R)-Tetrahydro-3-(trifluoroacetyl)-2H-pyran-2-one; (R)-3-Trifluoroacetyltetrahydro-2H-pyran-2-one
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-2-One, Tetrahydro-3-(Trifluoroacetyl)-, (+)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and development standards. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.