Description

Heptakis[6-(2-Aminoethylamino)-6-Deoxy]-β-Cyclodextrin is a highly functionalized, water-soluble cyclodextrin derivative engineered for advanced molecular encapsulation and targeted delivery. This compound matters because its seven primary amine side chains provide unique cationic character and enhanced binding affinity, making it a powerful supramolecular host for anionic or hydrophobic guest molecules. It is critically needed by researchers and formulators in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications ranging from drug solubilization and gene delivery to chiral separation and sensor development. The product is supplied under strict quality control to ensure batch-to-batch consistency for your most demanding projects.

Application

• Pharmaceutical Solubilization & Delivery: Enhances the aqueous solubility, stability, and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Gene & Nucleic Acid Delivery: Serves as a non-viral vector component for complexing and delivering DNA, siRNA, or mRNA due to its cationic amine groups.
• Chiral Separation Media: Used as a chiral selector or stationary phase modifier in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for enantiomer resolution.
• Chemical Sensor & Catalyst Design: Acts as a building block for creating selective fluorescent sensors or as a scaffold for asymmetric catalysis.
• Protein Stabilization & Modification: Aids in stabilizing protein structures and can be used for site-specific protein conjugation.
• Environmental Remediation: Employed in the selective extraction and removal of organic pollutants or heavy metal ions from aqueous solutions.
• Cosmetic Formulations: Used to encapsulate and stabilize sensitive active ingredients in advanced skincare products.

Basic Information

Product Name	Heptakis[6-(2-Aminoethylamino)-6-Deoxy]-β-Cyclodextrin
CAS No.	183069-38-7
Molecular Formula	C56H112N14O28
Molecular Weight	~1473.6 g/mol
Synonyms	Heptakis(6-deoxy-6-(2-aminoethylamino))-β-cyclodextrin; 6A,6B,6C,6D,6E,6F,6G-Heptakis(2-aminoethylamino)-6A,6B,6C,6D,6E,6F,6G-heptadeoxy-β-cyclodextrin; 7-Per-(2-aminoethylamino)-β-cyclodextrin; Aminoethylamino-β-CD; Cationic β-Cyclodextrin; Heptakis-6-(2-aminoethylamino)-6-deoxy-β-cyclodextrin
EINECS	Contact for details

Quality Control

Our Heptakis[6-(2-Aminoethylamino)-6-Deoxy]-β-Cyclodextrin is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by NMR or titration), degree of substitution, residual solvent content, and specific rotation. Our quality commitment supports applications requiring reliable and reproducible performance in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (NMR/Titration)	≥ 95.0%
Degree of Substitution (DS)	6.5 - 7.0
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.