Description

6-Oxabicyclo[3.1.0]Hexane-3-Carboxylicacid,Ethylester,(1Alpha,3Alpha,5Alpha)-(9Ci) is a high-purity, specialized bicyclic oxirane ester compound valued for its unique constrained molecular architecture. This structure makes it a critical advanced pharmaceutical intermediate and a versatile chiral building block in sophisticated organic synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Serves as a precursor for creating novel herbicides, fungicides, and insecticides with enhanced stereoselective activity.
• Fine Chemical Production: Used in the synthesis of complex fragrances, flavors, and specialty polymers requiring specific three-dimensional geometry.
• Academic & Industrial Research: A valuable tool compound in medicinal chemistry and methodology development for ring-opening and cross-coupling reactions.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	6-Oxabicyclo[3.1.0]Hexane-3-Carboxylicacid,Ethylester,(1Alpha,3Alpha,5Alpha)-(9Ci)
CAS No.	183065-60-3
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	Ethyl (1α,3α,5α)-6-Oxabicyclo[3.1.0]hexane-3-carboxylate; Ethyl 6-Oxabicyclo[3.1.0]hexane-3-carboxylate; 6-Oxabicyclo[3.1.0]hexane-3-carboxylic Acid Ethyl Ester; Bicyclic Oxirane Ester; 3-Carbethoxy-6-oxabicyclo[3.1.0]hexane; (1R,3R,5R)-Ethyl 6-oxabicyclo[3.1.0]hexane-3-carboxylate; (1S,3S,5S)-Ethyl 6-oxabicyclo[3.1.0]hexane-3-carboxylate (enantiomer)
EINECS	Contact for details

Quality Control

Our 6-Oxabicyclo[3.1.0]Hexane-3-Carboxylicacid,Ethylester,(1Alpha,3Alpha,5Alpha)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be sensitive to moisture and strong bases; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.