Description

2H-Pyran-2-Carboxylicacid,3,4-Dihydro-4-Oxo-,Methylester,(2R)-(9Ci) is a high-purity, chiral organic compound belonging to the class of substituted pyran-2-carboxylate esters. This molecule serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the construction of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical control.
• Asymmetric Synthesis: Used as a building block in catalytic and stoichiometric asymmetric reactions to introduce the (2R)-configured dihydropyranone moiety.
• Agrochemical Research: Intermediate in the synthesis of new-generation herbicides, fungicides, or insecticides where specific stereochemistry impacts biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals requiring high enantiomeric purity.
• Academic & Contract Research: Valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Process Chemistry: Scalable intermediate for optimizing synthetic routes in kilo-lab and pilot plant settings for commercial production.

Basic Information

Product Name	2H-Pyran-2-Carboxylicacid,3,4-Dihydro-4-Oxo-,Methylester,(2R)-(9Ci)
CAS No.	183013-60-7
Molecular Formula	C7H8O4
Molecular Weight	156.14 g/mol
Synonyms	(R)-Methyl 4-oxo-3,4-dihydro-2H-pyran-2-carboxylate; (2R)-4-Oxo-3,4-dihydro-2H-pyran-2-carboxylic acid methyl ester; Methyl (R)-4-oxo-3,4-dihydro-2H-pyran-2-carboxylate; (R)-4-Oxo-3,4-dihydro-2H-pyran-2-carboxylic Acid Methyl Ester; (R)-Dihydro-4-oxo-2H-pyran-2-carboxylic Acid Methyl Ester; (2R)-Methyl 4-oxo-3,4-dihydro-2H-pyran-2-carboxylate; (R)-2H-Pyran-2-carboxylic acid, 3,4-dihydro-4-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Our 2H-Pyran-2-Carboxylicacid,3,4-Dihydro-4-Oxo-,Methylester,(2R)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting research and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.