Description

2H-Pyran-2-Carboxylicacid,Tetrahydro-4-Oxo-,Methylester,(S)-(9Ci) is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functionalized pyranone core make it a critical precursor for the development of complex, biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly those focused on asymmetric synthesis and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in projects targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infective agents.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and testing of new chiral catalysts and methodologies.
• Natural Product Synthesis: Used in the total synthesis of complex natural products containing tetrahydro-4H-pyran-4-one or related lactone motifs.
• Agrochemical Development: Employed as a building block in the research and synthesis of novel, stereochemically defined pesticides and herbicides.
• Flavor & Fragrance Chemistry: Acts as a precursor for the creation of sophisticated, chiral lactone-based aroma compounds.
• Material Science Research: Investigated as a monomer or functional additive for the synthesis of specialized polymers with unique optical or physical properties.

Basic Information

Product Name	2H-Pyran-2-Carboxylicacid,Tetrahydro-4-Oxo-,Methylester,(S)-(9Ci)
CAS No.	183013-53-8
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(S)-Tetrahydro-4-oxo-2H-pyran-2-carboxylic acid methyl ester; Methyl (S)-tetrahydro-4-oxo-2H-pyran-2-carboxylate; (S)-Methyl tetrahydro-4-oxo-2H-pyran-2-carboxylate; (S)-4-Oxotetrahydro-2H-pyran-2-carboxylic acid methyl ester; (S)-Methyl 4-oxotetrahydropyran-2-carboxylate; (S)-Tetrahydro-4-oxopyran-2-carboxylic acid methyl ester; (S)-Methyl 4-oxo-3,4,5,6-tetrahydro-2H-pyran-2-carboxylate
EINECS	Contact for details

Quality Control

Our 2H-Pyran-2-Carboxylicacid,Tetrahydro-4-Oxo-,Methylester,(S)-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to meet the stringent requirements of pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.