Description

4-Phenyltetrahydropyran-4-Carboxylic Acid is a versatile and synthetically valuable organic compound featuring a tetrahydropyran ring substituted with both a phenyl group and a carboxylic acid moiety. This unique structure makes it a crucial advanced pharmaceutical intermediate and a key building block in modern organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and insecticides, leveraging its complex ring system.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Building Block: Employed in the synthesis of flavors, fragrances, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry, including ring-forming reactions and functional group transformations.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or optical properties.

Basic Information

Product Name	4-Phenyltetrahydropyran-4-Carboxylic Acid
CAS No.	182491-21-0
Molecular Formula	C₁₃H₁₆O₃
Molecular Weight	220.26 g/mol
Synonyms	4-Phenyltetrahydro-2H-pyran-4-carboxylic Acid; 4-Carboxy-4-phenyltetrahydropyran; 4-Phenyl-4-tetrahydropyrancarboxylic Acid; 4-Phenyloxane-4-carboxylic Acid; 4-Phenyltetrahydropyran-4-carboxylic acid; 182491-21-0; 4-Phenyltetrahydro-2H-pyran-4-carboxylic acid; 4-Phenyl-4-(tetrahydro-2H-pyran-4-yl)carboxylic acid (common misnomer)
EINECS	Contact for details

Quality Control

Our production of 4-Phenyltetrahydropyran-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications to ensure the material meets your precise research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.