Description

tert-Butyl 2-(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Ylidene)-2-Hydroxyethylcarbamate is a sophisticated chemical intermediate featuring a protected carbamate group and a reactive dioxane-dione moiety. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a protected amino acid or peptide-like structure.
• Peptidomimetic Research: Serves as a versatile scaffold for designing and synthesizing peptidomimetics and other biologically active molecules that mimic natural peptides.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate complex heterocyclic systems.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, dyes, and advanced organic materials.
• Academic & Institutional R&D: A valuable reagent for universities and research institutions exploring new organic reactions and methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	tert-Butyl 2-(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Ylidene)-2-Hydroxyethylcarbamate
CAS No.	182352-25-6
Molecular Formula	C₁₃H₁₉NO₇
Molecular Weight	301.29 g/mol
Synonyms	5-[(2-{[(tert-Butoxy)carbonyl]amino}-1-hydroxyethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione; N-Boc-2-hydroxy-2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)ethanamine; tert-Butyl N-[2-hydroxy-2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)ethyl]carbamate; Meldrum's acid derivative, Boc-protected; Boc-AEDD; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 2-(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Ylidene)-2-Hydroxyethylcarbamate is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development and commercial projects requiring consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.