Description

(3-Amino-5-Methoxy-Benzofuran-2-Yl)-(4-Fluoro-Phenyl)-Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its benzofuran core structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. Pharmaceutical R&D departments and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates targeting central nervous system disorders, inflammatory diseases, and oncology.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Key precursor in academic and industrial research for constructing complex benzofuran-based molecular libraries.
• Medicinal Chemistry: Core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Tool Compound: Used in the development of probes and inhibitors for biological target validation.
• Fine Chemical Production: Serves as a specialized intermediate in custom synthesis and contract manufacturing for the life sciences industry.

Basic Information

Product Name	(3-Amino-5-Methoxy-Benzofuran-2-Yl)-(4-Fluoro-Phenyl)-Methanone
CAS No.	182124-33-0
Molecular Formula	C₁₆H₁₂FNO₃
Molecular Weight	285.27 g/mol
Synonyms	3-Amino-5-methoxy-2-benzofuryl 4-fluorophenyl ketone; 2-(4-Fluorobenzoyl)-5-methoxy-3-aminobenzofuran; 5-Methoxy-3-amino-2-(4-fluorobenzoyl)benzofuran; (3-Amino-5-methoxy-2-benzofuranyl)(4-fluorophenyl)methanone; 182124-33-0; Methanone, (3-amino-5-methoxy-2-benzofuranyl)(4-fluorophenyl)-; AKOS005258155
EINECS	Contact for details

Quality Control

Our (3-Amino-5-Methoxy-Benzofuran-2-Yl)-(4-Fluoro-Phenyl)-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere if specified.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.