Description

1-Amino-2-Methylenecyclopropanecarboxylic Acid (Hydrochloride) is a specialized, high-purity building block with a unique constrained cyclopropane structure. This compound matters as a key chiral synthon for the synthesis of complex, biologically active molecules, particularly in advanced pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel protease inhibitors, antiviral agents, and other small-molecule therapeutics.
• Peptidomimetics Research: Used to incorporate constrained, non-natural amino acid motifs into peptide analogs to enhance metabolic stability and binding affinity.
• Agrochemical Synthesis: Serves as a precursor in the development of new generation herbicides and plant growth regulators with unique modes of action.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to design and synthesize activity-based probes for studying enzyme function and mechanism.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	1-Amino-2-Methylenecyclopropanecarboxylic Acid (Hydrochloride)
CAS No.	181712-46-9
Molecular Formula	C5H8ClNO2
Molecular Weight	149.57 g/mol
Synonyms	2-Methylene-1-aminocyclopropane-1-carboxylic acid hydrochloride; (1-Amino-2-methylenecyclopropyl)formic acid hydrochloride; 1-AMCP hydrochloride; Cyclopropane amino acid derivative; 1-Amino-2-methylidenecyclopropane-1-carboxylic acid hydrochloride; 2-Methylenecyclopropane-1,1-dicarboxylic acid monoamide hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Amino-2-Methylenecyclopropanecarboxylic Acid (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.