Description

3-Chloro-4-Iodo-6-Methoxypyridazine is a halogenated pyridazine derivative, a versatile and highly functionalized heterocyclic building block. Its unique structure, featuring chlorine and iodine substituents, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its reactive halogen sites for further functionalization.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic electronic materials, and liquid crystals.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex molecular architectures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis services catering to the fine chemical and life science industries.

Basic Information

Item	Details
Product Name	3-Chloro-4-Iodo-6-Methoxypyridazine
CAS No.	181355-91-9
Molecular Formula	C5H4ClIN2O
Molecular Weight	270.45 g/mol
Synonyms	6-Methoxy-3-chloro-4-iodopyridazine; 3-Chloro-4-iodo-6-methoxypyridazine; 4-Iodo-3-chloro-6-methoxypyridazine; 3-Chloro-4-iodo-6-methoxy-1,2-diazine; Pyridazine, 3-chloro-4-iodo-6-methoxy-; 181355-91-9
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Iodo-6-Methoxypyridazine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.