Description

3-Bromo-5-Chlorobenzene-1,2-Diol is a halogenated dihydroxybenzene derivative, a versatile and high-purity chemical intermediate essential for advanced organic synthesis. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures in research and development. This compound is particularly valuable for pharmaceutical chemists and agrochemical researchers developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates with halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the bromo and chloro substituents can enhance biological activity.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Dyestuff and Pigment Intermediate: Functions as a starting material for synthesizing complex halogenated dyes and high-performance pigments.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Item	Details
Product Name	3-Bromo-5-Chlorobenzene-1,2-Diol
CAS No.	180995-18-0
Molecular Formula	C6H4BrClO2
Molecular Weight	223.45 g/mol
Synonyms	3-Bromo-5-chloropyrocatechol; 3-Bromo-5-chloro-1,2-benzenediol; 1,2-Dihydroxy-3-bromo-5-chlorobenzene; 5-Chloro-3-bromobenzene-1,2-diol; 5-Chloro-3-bromocatechol; 3-Bromo-5-chlorocatechol; 2-Bromo-6-chlorobenzene-1,4-diol (isomer reference); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Chlorobenzene-1,2-Diol is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) with detailed results from HPLC, NMR, and GC-MS to verify identity, purity, and impurity profiles. Our quality commitment ensures consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.