Description

Methanimidamide, n-(1,2-Dihydroxyethyl)-N,n-Dimethyl-, [R-(E)]- (9Ci) CAS NO 180889-34-3 is a chiral amidine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a versatile and sophisticated building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring high stereochemical purity and functional group diversity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel herbicides and pesticides with specific stereochemical activity.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Bioconjugation Chemistry: Employed in the modification of biomolecules due to its reactive amidine functionality.
• Polymer Science: Serves as a monomer or cross-linking agent for producing specialty polymers with unique properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.

Basic Information

Product Name	Methanimidamide, n-(1,2-Dihydroxyethyl)-N,n-Dimethyl-, [R-(E)]- (9Ci)
CAS No.	180889-34-3
Molecular Formula	C7H16N2O2
Molecular Weight	160.22 g/mol
Synonyms	(R,E)-N-(1,2-Dihydroxyethyl)-N,N-dimethylmethanimidamide; (R,E)-1,2-Dihydroxy-N,N-dimethyl-N'-(1-hydroxyethyl)formamidine; 2-[(E)-Dimethylamino(imino)methyl]amino-1-ethanol, (2R)-; (2R)-2-[(E)-Dimethylcarbamimidamido]ethanol; N-(1,2-Dihydroxyethyl)-N,N-dimethylformamidine, (R,E)-; A chiral dihydroxyethyl dimethylamidine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are provided, detailing results from analytical methods including HPLC, NMR, and optical rotation. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.