Description

Methanimidamide, n-(1,2-Dihydroxyethyl)-N,n-Dimethyl-, [R-(E)]- (9Ci) is a specialized chiral amidine derivative with a defined stereochemistry, identified by CAS number 180889-29-6. This compound is valued for its role as a high-purity synthetic intermediate in the development of complex organic molecules, particularly in regulated industries where structural precision is critical. It is primarily sought by research and development teams in the pharmaceutical and fine chemical sectors for applications in asymmetric synthesis and the manufacture of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in stereoselective reactions to construct complex molecules with high enantiomeric purity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, agrochemicals, and advanced materials.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibitors and receptor ligands.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	Methanimidamide, n-(1,2-Dihydroxyethyl)-N,n-Dimethyl-, [R-(E)]- (9Ci)
CAS No.	180889-29-6
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	(R,E)-N-(1,2-Dihydroxyethyl)-N,N-dimethylmethanimidamide; (R,E)-1,2-Dihydroxy-N,N-dimethyl-1-ethanaminecarboximidamide; 1,2-Dihydroxy-N,N-dimethyl-1-ethanaminecarboximidamide, (R,E)-; Amidoxime derivative; Chiral amidine; N,N-Dimethyl-N'-(1,2-dihydroxyethyl)formamidine (R,E)-isomer
EINECS	Contact for details

Quality Control

Our production of Methanimidamide, n-(1,2-Dihydroxyethyl)-N,n-Dimethyl-, [R-(E)]- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to confirm identity, stereochemical purity, and assay. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We operate under a quality management system and can support development projects requiring compliance with cGMP or other regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.