Description

Toluene-4-Sulfonic Acid 4-tert-Butoxycarbonylamino-Butyl Ester is a specialized chemical building block primarily used as a key intermediate in organic synthesis. This compound matters for its role in introducing protected amino functionalities and facilitating specific coupling reactions in complex molecule construction. It is needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the preparation of amino acid derivatives and peptide fragments where the tert-butoxycarbonyl (Boc) group serves as a protecting group for amines.
• Agrochemical Synthesis: Employed as a precursor in the development and production of novel pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of specialized polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and labeled compounds for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	Toluene-4-Sulfonic Acid 4-tert-Butoxycarbonylamino-Butyl Ester
CAS No.	180851-50-7
Molecular Formula	C₁₆H₂₅NO₅S
Molecular Weight	343.44 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]butyl 4-methylbenzenesulfonate; 4-(Boc-amino)butyl tosylate; N-Boc-4-aminobutyl tosylate; 4-(N-Boc-amino)butyl p-toluenesulfonate; p-Toluenesulfonic acid 4-[(tert-butoxycarbonyl)amino]butyl ester; 1-[(tert-Butoxycarbonyl)amino]-4-[(4-methylphenyl)sulfonyl]oxybutane; Boc-4-aminobutyl tosylate; Tosyloxybutyl Boc-amine
EINECS	Contact for details

Quality Control

Our Toluene-4-Sulfonic Acid 4-tert-Butoxycarbonylamino-Butyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.