Description

1,2,3-Tri-o-Benzoyl-α-L-Fucopyranose, Trichloroacetimidate is a sophisticated glycosyl donor, a key building block in synthetic carbohydrate chemistry. This compound is specifically engineered for the stereoselective construction of complex oligosaccharides and glycoconjugates, offering high reactivity and excellent anomeric control. It is an essential reagent for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of carbohydrate-based drugs, vaccines, and diagnostic tools.

Application

• Glycosylation Reactions: A critical donor for the stereoselective synthesis of α-L-fucose-containing oligosaccharides.
• Pharmaceutical Intermediates: Used in the research and production of novel therapeutics, including anti-inflammatory, anti-cancer, and anti-metastatic agents.
• Glycoconjugate Vaccine Development: Serves as a key precursor for synthesizing antigenic carbohydrate moieties for conjugate vaccines.
• Glycobiology Research: An indispensable tool for studying fucose-mediated biological processes such as cell signaling, immune response, and pathogen recognition.
• Synthesis of Natural Products: Employed in the total synthesis of complex natural products that contain L-fucose residues.
• Diagnostic Reagent Synthesis: Used to create labeled glycans or probes for diagnostic assays and imaging.

Basic Information

Item	Detail
Product Name	1,2,3-Tri-o-Benzoyl-α-L-Fucopyranose, Trichloroacetimidate
CAS No.	180476-30-6
Molecular Formula	C34H30Cl3NO8
Molecular Weight	695.96 g/mol
Synonyms	1,2,3-Tri-O-benzoyl-α-L-fucopyranosyl trichloroacetimidate; α-L-Fucopyranose, 1,2,3-tris-O-(phenylcarbonyl)-, 1-(2,2,2-trichloroethanimidate); Trichloroacetimidate glycosyl donor; Fucosyl trichloroacetimidate donor; L-Fucose trichloroacetimidate derivative; Glycosylating agent for L-fucose; 2,3,4-Tri-O-benzoyl-α-L-fucopyranosyl trichloroacetimidate (alternative numbering)
EINECS	Contact for details

Quality Control

Every batch of 1,2,3-Tri-o-Benzoyl-α-L-Fucopyranose, Trichloroacetimidate is produced and tested under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. We provide comprehensive analytical data, including HPLC purity, NMR confirmation, and optical rotation. A detailed Certificate of Analysis (COA) is supplied with each shipment to guarantee it meets the stringent requirements for research and cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent decomposition. Keep container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.