Description

1,4,7,10-Benzotetraoxacyclododecin-12-Carboxylic Acid, 2,3,5,6,8,9-Hexahydro-, Ethyl Ester is a complex macrocyclic ester derivative, valued as a key synthetic intermediate and building block in advanced organic chemistry. Its unique polyether-fused structure makes it significant for the development of specialized ligands, catalysts, and functional materials. This high-purity compound is primarily needed by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and material science.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for complex macrocyclic drug candidates.
• Ligand Synthesis: Used in the development of specialized crown ether-like ligands for metal ion complexation and catalysis.
• Material Science Research: Acts as a building block for creating polymers and advanced organic materials with specific host-guest properties.
• Agrochemical Development: Employed in the research and synthesis of new-generation herbicides or plant growth regulators with targeted activity.
• Chemical Research: Utilized in academic and industrial laboratories for methodological studies in organic synthesis and supramolecular chemistry.
• Catalyst Design: Functions as a scaffold for constructing asymmetric catalysts used in enantioselective synthesis.

Basic Information

Product Name	1,4,7,10-Benzotetraoxacyclododecin-12-Carboxylic Acid, 2,3,5,6,8,9-Hexahydro-, Ethyl Ester
CAS No.	180475-66-5
Molecular Formula	C₁₅H₂₀O₆
Molecular Weight	296.32 g/mol
Synonyms	Ethyl 2,3,5,6,8,9-hexahydro-1,4,7,10-benzotetraoxacyclododecine-12-carboxylate; 12-Carbethoxy-2,3,5,6,8,9-hexahydro-1,4,7,10-benzotetraoxacyclododecin; Hexahydrobenzotetraoxacyclododecin-12-carboxylic acid ethyl ester; Benzotetraoxacyclododecin ethyl ester derivative; Macrocyclic polyether ester; CAS 180475-66-5
EINECS	Contact for details

Quality Control

Our 1,4,7,10-Benzotetraoxacyclododecin-12-Carboxylic Acid, 2,3,5,6,8,9-Hexahydro-, Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.