Description

((1R,4R)-4-((tert-Butoxycarbonylamino)Methyl)Cyclohexyl)Methyl Methanesulfonate is a high-purity, chiral building block essential for advanced pharmaceutical synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), enabling precise stereochemical control. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex therapeutic molecules, particularly in oncology and neurology.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for constructing complex drug candidates in medicinal chemistry.
• API Synthesis: Used in the multi-step synthesis of novel Active Pharmaceutical Ingredients (APIs), especially those targeting specific biological pathways.
• Peptidomimetic Research: Serves as a building block for creating peptidomimetics and other bioactive molecules with cyclohexyl scaffolds.
• Chemical Biology Probes: Employed in the development of labeled probes and tool compounds for target identification and validation studies.
• Process Chemistry Development: Utilized in route scouting and optimization for scalable GMP manufacturing of pharmaceutical compounds.

Basic Information

Product Name	((1R,4R)-4-((tert-Butoxycarbonylamino)Methyl)Cyclohexyl)Methyl Methanesulfonate
CAS No.	180046-36-0
Molecular Formula	C15H29NO5S
Molecular Weight	335.46 g/mol
Synonyms	(1R,4R)-4-[[(tert-Butoxycarbonyl)amino]methyl]cyclohexylmethyl methanesulfonate; (1R,4R)-4-((Boc-amino)methyl)cyclohexylmethyl mesylate; (1R,4R)-N-Boc-4-(aminomethyl)cyclohexylmethyl methanesulfonate; trans-4-((tert-Butoxycarbonylamino)methyl)cyclohexylmethyl methanesulfonate; (1R,4R)-Boc-Amc-OH Mesylate Ester; (1R,4R)-4-(Boc-aminomethyl)cyclohexylmethyl mesylate; Cyclohexanemethanol, 4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-, methanesulfonate, (1R,4R)-
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Quality Control

Our ((1R,4R)-4-((tert-Butoxycarbonylamino)Methyl)Cyclohexyl)Methyl Methanesulfonate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical development. All batches are supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.