Description

1-Bromo-5-Chloro-4-Methoxy-2-Methylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its precisely positioned functional groups, which enable selective cross-coupling and substitution reactions critical for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogen and methoxy substituents.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Essential for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reaction pathways and creating novel heterocyclic compounds.
• Dye and Pigment Intermediate: Acts as a precursor in the manufacture of complex organic dyes and colorants.

Basic Information

Product Name	1-Bromo-5-Chloro-4-Methoxy-2-Methylbenzene
CAS No.	179897-95-1
Molecular Formula	C8H8BrClO
Molecular Weight	235.51 g/mol
Synonyms	2-Bromo-4-Chloro-5-Methoxytoluene; 4-Bromo-2-Chloro-5-Methylanisole; 5-Bromo-2-Chloro-4-Methoxytoluene; 1-Bromo-5-chloro-4-methoxy-2-methyl-benzene; Benzene, 1-bromo-5-chloro-4-methoxy-2-methyl-; Toluene, 2-bromo-4-chloro-5-methoxy-; 2-Methyl-4-methoxy-5-chlorobromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-5-Chloro-4-Methoxy-2-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.