Description

2-Amino-2-(4-Chlorophenyl)Ethanol is a versatile chiral amino alcohol building block featuring both amino and hydroxyl functional groups on a chlorinated aromatic backbone. This compound matters for its critical role as a key intermediate in the synthesis of complex pharmaceutical molecules, particularly in the development of active pharmaceutical ingredients (APIs) and chiral catalysts. Industries that need it include pharmaceutical R&D, fine chemical manufacturing, and academic research laboratories focused on asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various APIs, including potential candidates for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, such as hydrogenation and epoxidation.
• Fine Chemical Synthesis: Serves as a building block for the production of complex agrochemicals, dyes, and specialty polymers.
• Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and developing novel chiral compounds.
• Resolution Agent: Can be utilized in the resolution of racemic mixtures due to its chiral center.

Basic Information

Product Name	2-Amino-2-(4-Chlorophenyl)Ethanol
CAS No.	179811-64-4
Molecular Formula	C8H10ClNO
Molecular Weight	171.62 g/mol
Synonyms	2-Amino-2-(4-chlorophenyl)ethan-1-ol; (R/S)-2-Amino-2-(4-chlorophenyl)ethanol; 4-Chloro-α-(aminomethyl)benzyl alcohol; 1-(4-Chlorophenyl)-2-aminoethanol; 2-(4-Chlorophenyl)-2-aminoethanol; 4-Chloro-β-amino-α-phenethyl alcohol; Amino(4-chlorophenyl)methanol (amino-methyl derivative); p-Chloro-α-(aminomethyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(4-Chlorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.