Description

4-(3-Bromophenyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid is a high-purity brominated heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel small-molecule drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the bromophenyl and tetrahydropyran motifs contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) due to its carboxylic acid functionality and rigid structure.
• Material Science Research: Employed in the synthesis of specialty polymers and organic electronic materials requiring brominated aromatic components.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags used in biochemical assay development.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(3-Bromophenyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid
CAS No.	179420-77-0
Molecular Formula	C12H13BrO3
Molecular Weight	285.14 g/mol
Synonyms	4-(3-Bromophenyl)oxane-4-carboxylic acid; 4-(3-Bromophenyl)tetrahydropyran-4-carboxylic acid; 3-Bromo-α,α-pentamethylenebenzenecetic acid; 4-(3-Bromophenyl)-4-carboxytetrahydropyran; 4-(m-Bromophenyl)tetrahydro-2H-pyran-4-carboxylic Acid; 179420-77-0; 4-(3-Bromophenyl)tetrahydropyran-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of 4-(3-Bromophenyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical specifications. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, and our quality system is designed to meet the rigorous demands of global regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.