Description

Ethyl 2-(2,4-Difluoro-5-Nitrophenoxy)Acetate is a high-purity, specialized organic intermediate featuring a difluoro-nitrophenoxy core structure. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a difluorinated aromatic system.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the nitrophenoxy moiety is integral to biological activity.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Dye & Pigment Intermediate: Serves as a starting material for synthesizing complex fluorinated dyes and functional colorants.
• Cross-Coupling Reactions: Substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	Ethyl 2-(2,4-Difluoro-5-Nitrophenoxy)Acetate
CAS No.	179011-36-0
Molecular Formula	C10H9F2NO5
Molecular Weight	261.18 g/mol
Synonyms	Ethyl (2,4-difluoro-5-nitrophenoxy)acetate; Acetic acid, 2-(2,4-difluoro-5-nitrophenoxy)-, ethyl ester; 2,4-Difluoro-5-nitrophenoxyacetic Acid Ethyl Ester; 5-Nitro-2,4-difluorophenoxyacetic Acid Ethyl Ester; Ethyl 2,4-Difluoro-5-nitrophenoxyacetate; Ethyl O-(2,4-difluoro-5-nitrophenyl)glycolate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2,4-Difluoro-5-Nitrophenoxy)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.