Description

Cyclopropanecarboxylic Acid, 2-(1-Oxobutyl)-, trans- (9Ci) is a specialized chiral cyclopropane derivative that serves as a valuable synthetic intermediate. Its unique trans-configured cyclopropane ring fused with a butyryl side chain makes it a critical building block for constructing complex molecular architectures with defined stereochemistry. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the preparation of advanced pesticides and herbicides, where the cyclopropane moiety can impart specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Building block for novel polymers and liquid crystals, leveraging the rigidity and angle strain of the cyclopropane ring.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and labeled compounds for studying biological mechanisms and pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Item	Detail
Product Name	Cyclopropanecarboxylic Acid, 2-(1-Oxobutyl)-, trans- (9Ci)
CAS No.	178683-13-1
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	trans-2-Butyrylcyclopropanecarboxylic Acid; (1R,2R)-2-Butyrylcyclopropane-1-carboxylic Acid; (1S,2S)-2-Butyrylcyclopropane-1-carboxylic Acid; 2-Butanoylcyclopropanecarboxylic Acid, trans-; trans-2-(1-Oxobutyl)cyclopropanecarboxylic Acid; 2-Butyryl-1-cyclopropanecarboxylic Acid, trans-; Cyclopropanecarboxylic acid, 2-butyryl-, trans-
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarboxylic Acid, 2-(1-Oxobutyl)-, trans- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as chiral purity, chemical purity, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, temperatures between 2°C and 8°C are recommended to maintain optimal stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.