Description

1,4-Dichlorophthalazine-6-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both chlorine and nitrile substituents on the phthalazine core, makes it a versatile precursor for constructing complex nitrogen-containing scaffolds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel phthalazine-based drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic reactivity.
• Material Science Research: Serves as a precursor for the synthesis of specialized dyes, pigments, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for biochemical research.
• Ligand and Catalyst Development: Acts as a starting material for creating novel chelating ligands and organocatalysts.
• Custom Synthesis Building Block: Supplied to fine chemical and CRO/CMO companies for bespoke synthesis projects requiring specific halogenated nitrile intermediates.

Basic Information

Product Name	1,4-Dichlorophthalazine-6-Carbonitrile
CAS No.	178308-61-7
Molecular Formula	C9H3Cl2N3
Molecular Weight	224.05 g/mol
Synonyms	6-Cyano-1,4-dichlorophthalazine; 1,4-Dichloro-6-cyanophthalazine; 1,4-Dichlorophthalazine-6-carbonitrile; Phthalazine-6-carbonitrile, 1,4-dichloro-; 178308-61-7; 1,4-Dichloro-6-phthalazinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 1,4-Dichlorophthalazine-6-Carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.