Description

2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid is a specialized organic compound featuring a diphenylpropanoic acid core structure with hydroxy and methoxy substituents, making it a valuable chiral building block and intermediate. This compound matters for its role in facilitating the synthesis of complex molecules, particularly in the pharmaceutical sector where precise stereochemistry is critical. It is primarily needed by research chemists and process development scientists in pharmaceutical, agrochemical, and advanced material industries for creating active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where its specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals due to its rigid, aromatic structure.
• Academic and R&D Laboratories: A valuable reference standard and starting material for methodological studies in organic synthesis and medicinal chemistry.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid
CAS No.	178306-51-9
Molecular Formula	C₁₆H₁₆O₄
Molecular Weight	272.30 g/mol
Synonyms	3,3-Diphenyl-2-hydroxy-3-methoxypropanoic Acid; α-Hydroxy-β-methoxy-β,β-diphenylpropionic Acid; 2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid; HMDPA; (RS)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid; DL-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid; β-Methoxy-α-hydroxy-β,β-diphenylpropanoic Acid
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.