Description

Benzofuran-4-Yl Trifluoromethanesulfonate CAS NO 177734-79-1 is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in its triflate group, which serves as an excellent leaving group, enabling efficient cross-coupling reactions and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery and development pipelines.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions such as Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Organic Synthesis Building Block: Facilitates the introduction of the benzofuran moiety into complex molecular architectures in academic and industrial R&D.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and molecular recognition studies.

Basic Information

Item	Detail
Product Name	Benzofuran-4-Yl Trifluoromethanesulfonate
CAS No.	177734-79-1
Molecular Formula	C10H5F3O4S
Molecular Weight	278.21 g/mol
Synonyms	4-Benzofuranyl Triflate; 4-Benzofuranyl Trifluoromethanesulfonate; Benzofuran-4-yl Triflate; 4-(Trifluoromethanesulfonyloxy)benzofuran; 1-Benzofuran-4-yl trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our Benzofuran-4-Yl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every lot upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.