Description

6,8-Dibromo-2H-Chromene-3-Carboxylic Acid Methyl Ester is a high-purity, functionalized chromene derivative that serves as a versatile and critical synthetic building block in advanced organic chemistry. Its value lies in its unique brominated chromene scaffold, which is essential for constructing complex molecular architectures with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical development, and materials science for the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or inflammatory pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in high-throughput screening.
• Agrochemical Development: Serves as a building block for creating new pesticides and herbicides with enhanced efficacy.
• Organic Synthesis: Employed in cyclization reactions and as a substrate for further functionalization (e.g., Suzuki coupling, nucleophilic substitution) to create diverse chromene-based compounds.
• Material Science Precursor: Potential intermediate for the development of organic light-emitting diodes (OLEDs) or nonlinear optical (NLO) materials due to the chromene core.

Basic Information

Product Name	6,8-Dibromo-2H-Chromene-3-Carboxylic Acid Methyl Ester
CAS No.	177496-81-0
Molecular Formula	C11H8Br2O3
Molecular Weight	348.0 g/mol
Synonyms	Methyl 6,8-dibromo-2H-chromene-3-carboxylate; 6,8-Dibromo-2H-1-benzopyran-3-carboxylic acid methyl ester; 2H-1-Benzopyran-3-carboxylic acid, 6,8-dibromo-, methyl ester; 6,8-Dibromochromene-3-carboxylic acid methyl ester; Methyl 6,8-dibromo-2H-1-benzopyran-3-carboxylate
EINECS	Contact for details

Quality Control

Our 6,8-Dibromo-2H-Chromene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.