Description

Ethanone, 1-(2,2,3-Trimethylcyclobutyl)-, (1S-Cis)- (9Ci) is a high-purity chiral ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the fragrance and pharmaceutical sectors, where its defined stereochemistry and unique cyclobutyl structure are critical for imparting specific olfactory or biological properties. Industries that require this product include fine chemical manufacturers, R&D laboratories, and producers of specialty aroma chemicals and active pharmaceutical ingredients (APIs).

Application

• Fragrance and Flavor Intermediate: Serves as a crucial precursor for synthesizing novel musk compounds and other specialty aroma molecules with complex, woody, or amber notes.
• Pharmaceutical Research: Used as a chiral synthon in the discovery and development of new therapeutic agents, leveraging its rigid cyclobutane scaffold.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex natural products and exploring new chemical spaces in medicinal chemistry.
• Agrochemical Intermediates: Potential use in the synthesis of advanced crop protection agents with specific stereochemical requirements.
• Material Science Precursor: Can be utilized in the development of specialty polymers or advanced organic materials requiring specific molecular architectures.

Basic Information

Product Name	Ethanone, 1-(2,2,3-Trimethylcyclobutyl)-, (1S-Cis)- (9Ci)
CAS No.	177316-73-3
Molecular Formula	C9H16O
Molecular Weight	140.22 g/mol
Synonyms	(1S-cis)-1-(2,2,3-Trimethylcyclobutyl)ethanone; 1-(2,2,3-Trimethylcyclobutyl)ethanone, (1S-cis)-; 2,2,3-Trimethylcyclobutyl methyl ketone; (1S,2R)-1-(2,2,3-Trimethylcyclobutyl)ethanone; cis-1-(2,2,3-Trimethylcyclobutyl)ethanone; CAS 177316-73-3; Chiral Trimethylcyclobutyl Methyl Ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2,2,3-Trimethylcyclobutyl)-, (1S-Cis)- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, identity confirmation by IR and NMR spectroscopy, and determination of chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.