Description

N2,N3-Bis-(tert-Butyloxycarbonyl)-1,5,10,14-Tetra-Aza-Quatrodecane is a specialized Boc-protected tetraamine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing orthogonal protection for amine functionalities, enabling the precise, sequential construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, particularly in the synthesis of peptide mimetics, macrocyclic compounds, and sophisticated drug candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates requiring complex polyamine backbones.
• Peptidomimetic Chemistry: Used to construct non-peptide scaffolds that mimic the structure and function of natural peptides for therapeutic applications.
• Macrocycle Synthesis: Serves as a versatile linker or spacer unit in the preparation of macrocyclic compounds for drug discovery and materials science.
• Ligand and Chelator Development: Building block for creating multidentate ligands and chelating agents used in catalysis and metal ion sequestration.
• Polymer Chemistry: Monomer for the synthesis of specialized polyamides and polymers with tailored amine functionality.
• Bioconjugation: Useful in creating cross-linking agents and spacers for attaching molecules to surfaces or biomolecules.

Basic Information

Product Name	N2,N3-Bis-(tert-Butyloxycarbonyl)-1,5,10,14-Tetra-Aza-Quatrodecane
CAS No.	177213-61-5
Molecular Formula	C26H52N4O4
Molecular Weight	484.72 g/mol
Synonyms	1,5,10,14-Tetraazatetradecane, N2,N3-Bis[(1,1-dimethylethoxy)carbonyl]-; N2,N3-Bis-Boc-1,5,10,14-tetraazatetradecane; N2,N3-Di-Boc-spermine; Boc2-Spermine; 1,14-Diamino-4,11-diaza-3,12-dioxotetradecane, N2,N3-Bis(tert-butoxycarbonyl)-; Tetra-Boc Protected Tetraamine Derivative
EINECS	Contact for details

Quality Control

Our N2,N3-Bis-(tert-Butyloxycarbonyl)-1,5,10,14-Tetra-Aza-Quatrodecane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.