Description

2-Propanone, 1-(Tetrahydro-2-Furanyl)-, (R)- (9Ci) is a chiral ketone building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex, stereochemically defined molecules, particularly in the pharmaceutical sector. Industries requiring high-purity chiral synthons for drug discovery, process development, and fine chemical manufacturing will find this product essential for their R&D and production needs.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to introduce the tetrahydrofuran moiety with defined (R)-configuration.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: Serves as a valuable reagent in methodological development and catalysis studies within organic chemistry laboratories.
• Agrochemical Synthesis: Potential intermediate for creating chiral compounds used in advanced crop protection agents.

Basic Information

Product Name	2-Propanone, 1-(Tetrahydro-2-Furanyl)-, (R)- (9Ci)
CAS No.	177182-58-0
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	(R)-1-(Tetrahydrofuran-2-yl)propan-2-one; (R)-1-(Tetrahydro-2-furanyl)-2-propanone; (R)-Tetrahydrofurfuryl Acetone; (R)-THFA; (R)-1-(Oxolan-2-yl)propan-2-one; (R)-2-Propanone, 1-(tetrahydro-2-furanyl)-; (R)-1-(Tetrahydrofuran-2-yl)acetone
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1-(Tetrahydro-2-Furanyl)-, (R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.