Description

[4-(Phenylmethoxy)Phenyl][4-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]Phenyl]-Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its complex diaryl ketone structure with protective groups. This compound is critical for the synthesis of complex organic molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for creating novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Acts as a protected intermediate for the construction of complex diaryl ketone and biphenyl-based molecular frameworks.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific aromatic architectures.

Basic Information

Product Name	[4-(Phenylmethoxy)Phenyl][4-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]Phenyl]-Methanone
CAS No.	176671-74-2
Molecular Formula	C25H24O4
Molecular Weight	388.46 g/mol
Synonyms	4-(Benzyloxy)phenyl[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]methanone; [4-(Benzyloxy)phenyl]{4-[(oxan-2-yl)oxy]phenyl}methanone; Methanone, [4-(phenylmethoxy)phenyl][4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-; THP-Protected Benzophenone Derivative; Diarylmethanone Intermediate
EINECS	Contact for details

Quality Control

Our production of [4-(Phenylmethoxy)Phenyl][4-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]Phenyl]-Methanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.