Description

1-Bromo-4-Isopropoxy-2-Methoxybenzene is a high-purity, synthetically valuable aromatic ether derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its substituted benzene core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: Functions as a reliable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions due to the bromine substituent.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	1-Bromo-4-Isopropoxy-2-Methoxybenzene
CAS No.	176391-61-0
Molecular Formula	C10H13BrO2
Molecular Weight	245.11 g/mol
Synonyms	4-Bromo-1-isopropoxy-2-methoxybenzene; 2-Methoxy-4-bromophenyl isopropyl ether; 1-Bromo-2-methoxy-4-isopropoxybenzene; 4-Bromo-2-methoxyphenyl isopropyl ether; Isopropyl 4-bromo-2-methoxyphenyl ether; (4-Bromo-2-methoxyphenoxy)propane
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Isopropoxy-2-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and lot-to-lot consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.