Description

1-Cyclopropene-1-Methanol,2-Bromo-(9Ci) is a specialized brominated cyclopropene derivative, a high-value synthetic intermediate prized for its unique strained-ring reactivity. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research where its functional groups enable precise chemical transformations. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors for applications in medicinal chemistry and catalysis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring cyclopropane motifs.
• Agrochemical Research: Used in the development of new crop protection agents and herbicides, leveraging its reactive bromine and alcohol functionalities.
• Material Science: Serves as a precursor for functionalized monomers or cross-linking agents in the creation of specialty polymers with tailored properties.
• Organic Synthesis: A versatile reagent for cyclopropanation reactions, ring-opening polymerizations, and as a substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or biological pathways.
• Catalyst Ligand Synthesis: Acts as a starting material for the preparation of novel chiral or sterically hindered ligands used in asymmetric catalysis.

Basic Information

Product Name	1-Cyclopropene-1-Methanol,2-Bromo-(9Ci)
CAS No.	176167-13-8
Molecular Formula	C5H7BrO
Molecular Weight	163.01 g/mol
Synonyms	2-Bromo-1-cyclopropene-1-methanol; 2-Bromocycloprop-1-ene-1-methanol; (2-Bromocycloprop-1-en-1-yl)methanol; 1-Cyclopropene-1-methanol, 2-bromo-; 1-(Hydroxymethyl)-2-bromocyclopropene; Bromo(cyclopropenyl)methanol; 176167-13-8
EINECS	Contact for details

Quality Control

Our 1-Cyclopropene-1-Methanol,2-Bromo-(9Ci) is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from techniques including HPLC, GC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles for advanced chemical intermediates, ensuring reliable performance in your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactive functional groups, it is recommended to store under an inert atmosphere for long-term stability and to minimise decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.