Description

3-Fluoro-4-Methylbenzamidine Hydrochloride is a high-purity organic salt and a key benzamidine derivative used as a specialized building block in advanced chemical synthesis. Its value lies in providing a reactive amidine group and a substituted aromatic ring system, enabling the construction of complex molecules with targeted functionality. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of protease inhibitors, enzyme substrates, and novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of drug candidates, especially those targeting serine proteases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Biochemical Tool Compound: Serves as a precursor for enzyme inhibitors and labeled probes in biochemical assays and diagnostic research.
• Organic Synthesis: A versatile reagent for introducing the amidine functional group into complex molecular architectures.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	3-Fluoro-4-Methylbenzamidine Hydrochloride
CAS No.	175277-88-0
Molecular Formula	C8H10FN2•HCl
Molecular Weight	188.63 (Free base) / 225.09 (HCl salt)
Synonyms	4-Methyl-3-fluorobenzamidine hydrochloride; 3-Fluoro-4-methylbenzenecarboximidamide hydrochloride; 3-Fluoro-p-tolylamidine hydrochloride; (3-Fluoro-4-methylphenyl)methanimidamide hydrochloride; Benzamidine, 3-fluoro-4-methyl-, hydrochloride; Amidino-3-fluoro-4-methylbenzene hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methylbenzamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets exacting standards for research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.