Description

Rac-(1R,2R)-2-(4-Fluorophenyl)Cyclopropane-1-Carboxylic Acid is a high-purity chiral cyclopropane derivative, a key structural motif in advanced organic synthesis. This compound is valued for its role as a versatile and critical building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where the cyclopropane ring confers biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, especially in cyclopropanation and stereoselective transformations.

Basic Information

Product Name	Rac-(1R,2R)-2-(4-Fluorophenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	175275-74-8
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	(±)-(1R,2R)-2-(4-Fluorophenyl)cyclopropanecarboxylic Acid; rac-trans-2-(4-Fluorophenyl)cyclopropanecarboxylic Acid; trans-2-(p-Fluorophenyl)cyclopropanecarboxylic Acid; 2-(4-Fluorophenyl)cyclopropanecarboxylic Acid (racemic trans); 4-Fluorophenylcyclopropanecarboxylic Acid; FPC Acid; 175275-74-8
EINECS	Contact for details

Quality Control

Our Rac-(1R,2R)-2-(4-Fluorophenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.