Description

8-Chloro-3-(4-trifluoromethylphenyl)-1,2,4-triazolo[4,3-b]pyridazine is a high-value, heterocyclic organic compound featuring a fused triazolopyridazine core substituted with chloro and trifluoromethylphenyl groups. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the triazolopyridazine moiety.
• Medicinal Chemistry Building Block: Employed in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities and optimize lead compounds.
• Material Science Precursor: Investigated for the development of specialty chemicals and advanced materials, such as organic semiconductors or ligands for catalysis.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-specific projects and scale-up development.

Basic Information

Product Name	8-Chloro-3-(4-Trifluoromethylphenyl)-1,2,4-Triazolo[4,3-B]Pyridazine
CAS No.	175204-95-2
Molecular Formula	C13H6ClF3N4
Molecular Weight	310.66 g/mol
Synonyms	8-Chloro-3-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazine; 1,2,4-Triazolo[4,3-b]pyridazine, 8-chloro-3-[4-(trifluoromethyl)phenyl]-; 175204-95-2; 8-Chloro-3-(4-trifluoromethylphenyl)-1,2,4-triazolopyridazine; 8-Chloro-3-(p-trifluoromethylphenyl)-1,2,4-triazolo[4,3-b]pyridazine
EINECS	Contact for details

Quality Control

Our production of 8-Chloro-3-(4-trifluoromethylphenyl)-1,2,4-triazolo[4,3-b]pyridazine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical specifications. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.