Description

4-(Trifluoromethoxy)Phenoxyacetic Acid Hydrazide is a high-purity, specialized organic intermediate featuring a reactive hydrazide group and a trifluoromethoxy-substituted aromatic ring. This compound matters for its role as a critical building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, crop protection, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and plant growth regulators that leverage the trifluoromethoxy group for enhanced bioactivity and stability.
• Ligand and Chelator Preparation: Used to create specialized hydrazone-based ligands for metal catalysis or analytical chemistry applications.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for introducing specific aromatic and reactive groups into polymer backbones.
• Bioconjugation Chemistry: The reactive hydrazide moiety is utilized for site-specific conjugation with aldehydes and ketones in biopharmaceutical linker technology.
• Material Science Research: Intermediate in the development of organic electronic materials, liquid crystals, or advanced coatings.

Basic Information

Product Name	4-(Trifluoromethoxy)Phenoxyacetic Acid Hydrazide
CAS No.	175204-36-1
Molecular Formula	C9H9F3N2O3
Molecular Weight	250.18 g/mol
Synonyms	4-(Trifluoromethoxy)phenoxyacetohydrazide; [4-(Trifluoromethoxy)phenoxy]acetic acid hydrazide; 2-[4-(Trifluoromethoxy)phenoxy]acetohydrazide; Acetic acid, 2-[4-(trifluoromethoxy)phenoxy]-, hydrazide; 4-Trifluoromethoxyphenoxyacetic acid hydrazide
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Phenoxyacetic Acid Hydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.