Description

3,5-Bis(Trifluoromethyl)Benzenesulfonyl Guanidine is a high-value, multi-functional chemical building block characterized by its electron-withdrawing trifluoromethyl groups and reactive sulfonyl guanidine moiety. This compound matters for its role as a key intermediate in the synthesis of advanced pharmaceuticals, particularly in the development of protease inhibitors and other biologically active molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate unique physicochemical properties into their target compounds.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel drug candidates, especially in protease inhibitor research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the trifluoromethyl group enhances bioavailability and stability.
• Material Science: Serves as a monomer or additive for synthesizing specialty polymers with enhanced chemical resistance.
• Chemical Research: Employed in academic and industrial laboratories for exploring new reactions and catalytic processes involving sulfonyl guanidine chemistry.
• Ligand & Catalyst Development: Useful in the design of novel ligands for metal catalysis due to its strong electron-withdrawing and coordinating properties.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Benzenesulfonyl Guanidine
CAS No.	175136-69-3
Molecular Formula	C9H5F6N3O2S
Molecular Weight	333.21 g/mol
Synonyms	3,5-Bis(trifluoromethyl)benzenesulfonylguanidine; N-[[[3,5-Bis(trifluoromethyl)phenyl]sulfonyl]amino]methanimidamide; Guanidine, N-[[[3,5-bis(trifluoromethyl)phenyl]sulfonyl]amino]-; 3,5-Bis(trifluoromethyl)phenylsulfonylguanidine; 3,5-Di(trifluoromethyl)benzenesulfonylguanidine
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)Benzenesulfonyl Guanidine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.