Description

Methyl 3-[(Chlorosulfonyl)Methyl]Benzoate is a specialized organic synthesis intermediate featuring a reactive chlorosulfonyl group and a methyl benzoate ester. This compound is valued for its versatility as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those requiring sulfonamide or sulfonate ester functionalities.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the chlorosulfonyl group enables further derivatization.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Chemical Biology Probes: Utilized in the creation of activity-based probes and other tools for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	Methyl 3-[(Chlorosulfonyl)Methyl]Benzoate
CAS No.	174961-63-8
Molecular Formula	C9H9ClO4S
Molecular Weight	248.68 g/mol
Synonyms	3-[(Chlorosulfonyl)methyl]benzoic acid methyl ester; Methyl 3-(chlorosulfonylmethyl)benzoate; Benzoic acid, 3-[(chlorosulfonyl)methyl]-, methyl ester; Methyl m-[(chlorosulfonyl)methyl]benzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-[(Chlorosulfonyl)Methyl]Benzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.