Description

1-Bromo-2,3-Dichloro-5-Methoxybenzene is a halogenated anisole derivative serving as a versatile and high-value synthetic intermediate. Its precise substitution pattern makes it a critical building block for constructing complex molecular architectures in advanced chemical synthesis. This compound is primarily utilized by research institutions and industrial R&D departments focused on developing pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a specific halogenated aromatic core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the bromo and chloro substituents contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to introduce complex aryl groups.
• Dye and Pigment Manufacturing: Intermediate for producing specialized halogenated dyes and pigments with enhanced properties.
• Contract Research & Development (CRO/CMO): Supplied to custom synthesis organizations for client-directed research projects and scale-up processes.

Basic Information

Product Name	1-Bromo-2,3-Dichloro-5-Methoxybenzene
CAS No.	174913-19-0
Molecular Formula	C7H5BrCl2O
Molecular Weight	256.93 g/mol
Synonyms	2,3-Dichloro-5-methoxybromobenzene; 5-Bromo-2,3-dichloroanisole; 1-Bromo-2,3-dichloro-5-methoxybenzene; Benzene, 1-bromo-2,3-dichloro-5-methoxy-; 2,3-Dichloro-5-methoxy-1-bromobenzene; 3-Bromo-4,5-dichloroanisole; Bromo-dichloro-methoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,3-Dichloro-5-Methoxybenzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.