Description

Bdp R6G Carboxylic Acid is a high-purity, functionalized derivative of the BODIPY fluorophore family, designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and manufacturers requiring precise, covalent attachment of a bright, photostable fluorescent tag to biomolecules like proteins, peptides, and oligonucleotides. It is essential for professionals in biomedical research, diagnostic assay development, and advanced materials science who need reliable, high-performance fluorescent probes.

Application

• Bioconjugation and Probe Synthesis: Primary use as a reactive intermediate for covalently labeling antibodies, proteins, and other biomolecules with a red-emitting BODIPY fluorophore.
• Fluorescent Imaging Reagents: Key building block in the development of high-contrast fluorescent dyes for cellular imaging, flow cytometry, and microscopy (e.g., confocal, super-resolution).
• Diagnostic Assay Development: Used to create fluorescent tracers and detection reagents for ELISA, lateral flow assays, and other in vitro diagnostic (IVD) platforms.
• Chemical Biology & Drug Discovery: Employed in activity-based protein profiling (ABPP), target engagement studies, and the synthesis of fluorescently labeled small-molecule probes.
• Materials Science: Functional component for creating fluorescent sensors, smart polymers, and advanced optical materials where a carboxylic acid handle is required for further modification.
• Nucleic Acid Labeling: Conjugation to modified nucleotides or oligonucleotides for FISH (Fluorescence In Situ Hybridization) and real-time PCR applications.

Basic Information

Product Name	Bdp R6G Carboxylic Acid
CAS No.	174881-57-3
Molecular Formula	C₂₃H₂₁BF₂N₂O₂
Molecular Weight	406.23 g/mol
Synonyms	BODIPY R6G carboxylic acid; 4,4-Difluoro-5-(2-thienyl)-4-bora-3a,4a-diaza-s-indacene-3-propionic acid (BDP R6G); BDP FL; BDP 581/591 carboxylic acid; BODIPY 581/591 C3; 3-(5,5-Difluoro-7-(2-thienyl)-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)propanoic acid; BDP R6G acid; BODIPY® R6G C3
EINECS	Contact for details

Quality Control

Our Bdp R6G Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and functional testing for fluorescence quantum yield. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Desiccate for long-term storage. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Red to dark red solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Absorption (λmax)	581 ± 3 nm
Emission (λmax)	591 ± 3 nm
Extinction Coefficient (ε)	≥ 80,000 cm⁻¹M⁻¹
Fluorescence Quantum Yield (φ)	≥ 0.7 (Reference: Rhodamine 6G)
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.